![]() However, single end-group analysis is possible with a MALDI-TOF when you use the fragmentation possibility of a TOF/TOF instrument.įor copolymers again it’s only Polymerix which can do the analysis of the combined end-groups in the lower molecular weight range. You don't get single end-group analysis when using MALDI-TOF alone. In the end, you always get the combination of the end groups. Polymerix will make suggestions for the chemical composition of the combined end-groups depending on the pre-settings you choose. PolyTools will give you the answer right away as long as monomer and end-groups are defined in the program. Both Polymerix, and PolyTools can be used here. VS: For homopolymers it’s absolutely straightforward. Q: Is end-group analysis easy for homopolymers and copolymers? The Polymerix software can generate nice 2D plots of the distributions of the different monomers. ![]() In this case, you would want to use Polymerix software, rather than PolyTools. The typical mass range that you can analyze is up to approximately 5 kDa. At higher masses, the complexity of the copolymers is too high - there are just too many possible combinations of monomers. It's possible to analyze copolymers, it depends a bit on the mass range, of course. Q: Is it possible to analyze copolymers with MALDI-TOF? He joined Bruker in 1998 as MALDI application specialist and now has more than 20 years’ experience with various applications of MALDI-TOF mass spectrometry. During his Ph.D., he focused on the mass spectrometric analysis of conductive electrochemically generated synthetic polymers. Volker Sauerland studied chemistry at Christian-Albrechts-University in Kiel. LC-MS innovation: Improve analytical accuracyĭr. Which microbioreactor modules are best for you
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |